STAM2 Antikörper (AA 376-525)
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- Target Alle STAM2 Antikörper anzeigen
- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
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Bindungsspezifität
- AA 376-525
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STAM2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Signal transducing adapter molecule 2 protein (376-525AA)
- Isotyp
- IgG
- Top Product
- Discover our top product STAM2 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
- Andere Bezeichnung
- STAM2 (STAM2 Produkte)
- Synonyme
- Hbp antikoerper, STAM2A antikoerper, STAM2B antikoerper, 1200004O12Rik antikoerper, 5730456G07Rik antikoerper, BB145015 antikoerper, stam2 antikoerper, MGC52950 antikoerper, zgc:103628 antikoerper, signal transducing adaptor molecule 2 antikoerper, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antikoerper, signal transducing adaptor molecule 2 S homeolog antikoerper, STAM2 antikoerper, Stam2 antikoerper, stam2.S antikoerper, stam2 antikoerper
- Hintergrund
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Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).
Aliases: DKFZp564C047 antibody, Hbp antibody, Hrs-binding protein antibody, HSE1 homolog antibody, Signal transducing adapter molecule 2 antibody, Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, Signal transducing adaptor molecule 2A antibody, Signal transducing adaptor molecule 2B antibody, Signal transducing adaptor molecule antibody, STAM like protein containing SH3 and ITAM domains 2 antibody, STAM-2 antibody, Stam2 antibody, STAM2_HUMAN antibody, STAM2A antibody, STAM2B antibody
- UniProt
- O75886
- Pathways
- EGFR Signaling Pathway, EGFR Downregulation
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