STAM2 Antikörper

Produktnummer ABIN6265306

Produktdetails anti-STAM2 Antikörper

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: STAM2 Antibody detects endogenous levels of total STAM2

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human STAM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu STAM2

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Andere Bezeichnung: STAM2 (STAM2 Produkte)

Synonyme: Hbp antikoerper, STAM2A antikoerper, STAM2B antikoerper, 1200004O12Rik antikoerper, 5730456G07Rik antikoerper, BB145015 antikoerper, stam2 antikoerper, MGC52950 antikoerper, zgc:103628 antikoerper, signal transducing adaptor molecule 2 antikoerper, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antikoerper, signal transducing adaptor molecule 2 S homeolog antikoerper, STAM2 antikoerper, Stam2 antikoerper, stam2.S antikoerper, stam2 antikoerper

Hintergrund:

Description: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).

Gene: STAM2

Molekulargewicht: 58kDa

Gen-ID: 10254

UniProt: O75886

Pathways: EGFR Signaling Pathway, EGFR Downregulation