PHLDA3 Antikörper (AA 43-95)

Produktnummer ABIN7163671

Produktdetails anti-PHLDA3 Antikörper

Target: PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))

Bindungsspezifität: AA 43-95

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHLDA3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Pleckstrin homology-like domain family A member 3 protein (43-95AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PHLDA3

Target: PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))

Andere Bezeichnung: PHLDA3 (PHLDA3 Produkte)

Synonyme: TIH1 antikoerper, Tih1 antikoerper, si:dz182n13.5 antikoerper, zgc:92333 antikoerper, pleckstrin homology like domain family A member 3 antikoerper, pleckstrin homology like domain, family A, member 3 antikoerper, pleckstrin homology-like domain, family A, member 3 antikoerper, PHLDA3 antikoerper, Phlda3 antikoerper, phlda3 antikoerper

Hintergrund:

Background: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.

Aliases: PHLA3_HUMAN antibody, PHLDA 3 antibody, phlda3 antibody, Pleckstrin homology like domain family A member 2 antibody, Pleckstrin homology like domain family A member 3 antibody, Pleckstrin homology-like domain family A member 3 antibody, TDAG51/Ipl homolog 1 antibody, TDAG51/Ipl homologue 1 antibody, TIH 1 antibody, TIH1 antibody

UniProt: Q9Y5J5