Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PHLDA3 Antikörper (C-Term)

PHLDA3 Reaktivität: Human, Maus, Ratte ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258301
  • Target Alle PHLDA3 Antikörper anzeigen
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 21
    • 6
    • 6
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 18
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 19
    • 2
    Polyklonal
    Konjugat
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PHLDA3 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 8
    • 4
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Spezifität
    PHLDA3 Antibody detects endogenous levels of total PHLDA3.
    Homologie
    Pig,Rabbit
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human PHLDA3, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PHLDA3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Andere Bezeichnung
    PHLDA3 (PHLDA3 Produkte)
    Synonyme
    TIH1 antikoerper, Tih1 antikoerper, si:dz182n13.5 antikoerper, zgc:92333 antikoerper, pleckstrin homology like domain family A member 3 antikoerper, pleckstrin homology like domain, family A, member 3 antikoerper, pleckstrin homology-like domain, family A, member 3 antikoerper, PHLDA3 antikoerper, Phlda3 antikoerper, phlda3 antikoerper
    Hintergrund

    Description: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.

    Gene: PHLDA3

    Molekulargewicht
    14 kDa
    Gen-ID
    23612
    UniProt
    Q9Y5J5
Sie sind hier:
Kundenservice