MOB1A Antikörper (AA 2-216)

Produktnummer ABIN7160116

Produktdetails anti-MOB1A Antikörper

Target: MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))

Bindungsspezifität: AA 2-216

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MOB1A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human MOB kinase activator 1A protein (2-216AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:2000-1:5000, IHC:1:100-1:1000, IF:1:200-1:500, IP1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MOB1A

Target: MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))

Andere Bezeichnung: MOB1A (MOBKL1B Produkte)

Synonyme: mob1 antikoerper, mob4b antikoerper, MOB1A antikoerper, MOBK1B antikoerper, MOB1 antikoerper, mats1 antikoerper, mobk1b antikoerper, mobkl1b antikoerper, MOBKL1B antikoerper, wu:fv69d04 antikoerper, zgc:56189 antikoerper, C2orf6 antikoerper, MATS1 antikoerper, Mob4B antikoerper, 4022402H07Rik antikoerper, MOB4B antikoerper, Mobk1b antikoerper, Mobkl1b antikoerper, MOB kinase activator 1A L homeolog antikoerper, MOB kinase activator 1A antikoerper, MOB kinase activator 1A pseudogene antikoerper, mob1a.L antikoerper, MOB1A antikoerper, mob1a antikoerper, LOC712156 antikoerper, Mob1a antikoerper

Hintergrund:

Background: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38.

Aliases: B1, Mps One Binder kinase activator like 1B (yeast) antibody, C2orf6 antibody, Chromosome 2 open reading frame 6 antibody, FLJ10788 antibody, FLJ11595 antibody, MATS1 antibody, MOB kinase activator 1A antibody, MOB1 antibody, Mob1 alpha antibody, Mob1 homolog 1B antibody, MOB1 Mps One Binder homolog A antibody, MOB1 Mps One Binder kinase activator like 1B antibody, Mob1A antibody, MOB4B antibody, Mob4B protein antibody, MOBK1B antibody, Mobkl1b antibody, MOL1B_HUMAN antibody, Mps one binder kinase activator like 1B antibody, Mps one binder kinase activator-like 1B antibody, Protein Mob4B antibody

UniProt: Q9H8S9