MRAP2 Antikörper (AA 66-205)

Produktnummer ABIN7159225

Produktdetails anti-MRAP2 Antikörper

Target: MRAP2 (Melanocortin 2 Receptor Accessory Protein 2 (MRAP2))

Bindungsspezifität: AA 66-205

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRAP2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Melanocortin-2 receptor accessory protein 2 protein (66-205AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MRAP2

Target: MRAP2 (Melanocortin 2 Receptor Accessory Protein 2 (MRAP2))

Andere Bezeichnung: MRAP2 (MRAP2 Produkte)

Synonyme: BB633055 antikoerper, RGD1309873 antikoerper, C9H6ORF117 antikoerper, C6orf117 antikoerper, RP11-51G5.2 antikoerper, bA51G5.2 antikoerper, melanocortin 2 receptor accessory protein 2 antikoerper, Mrap2 antikoerper, MRAP2 antikoerper

Hintergrund:

Background: Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R), however, additional evidences are required in vivo.

Aliases: MRAP2 antibody, C6orf117 antibody, Melanocortin-2 receptor accessory protein 2 antibody, MC2R accessory protein 2 antibody

UniProt: Q96G30