MRAP2 Antikörper

Produktnummer ABIN7116150

Produktdetails anti-MRAP2 Antikörper

Target: MRAP2 (Melanocortin 2 Receptor Accessory Protein 2 (MRAP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRAP2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: melanocortin 2 receptor accessory protein 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu MRAP2

Target: MRAP2 (Melanocortin 2 Receptor Accessory Protein 2 (MRAP2))

Andere Bezeichnung: MRAP2 (MRAP2 Produkte)

Synonyme: BB633055 antikoerper, RGD1309873 antikoerper, C9H6ORF117 antikoerper, C6orf117 antikoerper, RP11-51G5.2 antikoerper, bA51G5.2 antikoerper, melanocortin 2 receptor accessory protein 2 antikoerper, Mrap2 antikoerper, MRAP2 antikoerper

Hintergrund: Synonyms:C6orf117 Background:Modulator of melanocortin receptor 4(MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP(By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin(ACTH) to MC2R. May also regulate activity of other melanocortin receptors(MC1R, MC3R and MC5R), however, additional evidences are required in vivo.

Gen-ID: 112609

UniProt: Q96G30