LDLRAP1 Antikörper (AA 59-308)
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- Target Alle LDLRAP1 Antikörper anzeigen
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
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Bindungsspezifität
- AA 59-308
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LDLRAP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Low density lipoprotein receptor adapter protein 1 protein (59-308AA)
- Isotyp
- IgG
- Top Product
- Discover our top product LDLRAP1 Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
- Andere Bezeichnung
- LDLRAP1 (LDLRAP1 Produkte)
- Synonyme
- ARH antikoerper, ARH1 antikoerper, ARH2 antikoerper, FHCB1 antikoerper, FHCB2 antikoerper, AA691260 antikoerper, Arh antikoerper, Arh1 antikoerper, RGD1563417 antikoerper, arh antikoerper, arh1 antikoerper, arh2 antikoerper, fhcb1 antikoerper, fhcb2 antikoerper, xptb antikoerper, LDLRAP1 antikoerper, ldlrap1 antikoerper, sb:cb50 antikoerper, zgc:56121 antikoerper, zgc:158745 antikoerper, low density lipoprotein receptor adaptor protein 1 antikoerper, low density lipoprotein receptor adaptor protein 1 L homeolog antikoerper, low density lipoprotein receptor adaptor protein 1 S homeolog antikoerper, low density lipoprotein receptor adaptor protein 1a antikoerper, low density lipoprotein receptor adaptor protein 1b antikoerper, LDLRAP1 antikoerper, Ldlrap1 antikoerper, ldlrap1 antikoerper, ldlrap1.L antikoerper, ldlrap1.S antikoerper, ldlrap1a antikoerper, ldlrap1b antikoerper
- Hintergrund
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Background: Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface.
Aliases: ARH antibody, ARH GENE antibody, ARH_HUMAN antibody, ARH1 antibody, ARH2 antibody, Autosomal recessive hypercholesterolemia protein antibody, DKFZp586D0624 antibody, FHCB1 antibody, FHCB2 antibody, LDL receptor adaptor protein antibody, Ldlrap1 antibody, Low density lipoprotein receptor adapter protein 1 antibody, MGC34705 antibody, OTTHUMP00000008526 antibody
- UniProt
- Q5SW96
- Pathways
- Lipid Metabolism
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