HECW1 Antikörper (AA 751-900) (HRP)

Produktnummer ABIN7151036

Produktdetails anti-HECW1 Antikörper (HRP)

Target: HECW1 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1))

Bindungsspezifität: AA 751-900

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HECW1 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase HECW1 protein (751-900AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HECW1

Target: HECW1 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1))

Andere Bezeichnung: HECW1 (HECW1 Produkte)

Synonyme: NEDL1 antikoerper, 9330116H24Rik antikoerper, AV273951 antikoerper, E130207I19Rik antikoerper, Nedl1 antikoerper, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 antikoerper, HECW1 antikoerper, Hecw1 antikoerper

Hintergrund:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

Aliases: C2 and WW domain-containing protein 1 antibody, E3 ubiquitin-protein ligase HECW1 antibody, HECT antibody, HECT type E3 ubiquitin ligase antibody, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 antibody, HECT, C2 and WW domain-containing protein 1 antibody, HECW 1 antibody, Hecw1 antibody, HECW1_HUMAN antibody, hNEDL1 antibody, NEDD4 like ubiquitin protein ligase 1 antibody, NEDD4-like E3 ubiquitin-protein ligase 1 antibody, NEDL1 antibody

UniProt: Q76N89