HECW1 Antikörper (Internal Region)
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- Target Alle HECW1 Antikörper anzeigen
- HECW1 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1))
- Bindungsspezifität
- Internal Region
- Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HECW1 Antikörper ist unkonjugiert
- Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- HECW1 Antibody detects endogenous levels of total HECW1.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HECW1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product HECW1 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- HECW1 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1))
- Andere Bezeichnung
- HECW1 (HECW1 Produkte)
- Synonyme
- NEDL1 antikoerper, 9330116H24Rik antikoerper, AV273951 antikoerper, E130207I19Rik antikoerper, Nedl1 antikoerper, HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 antikoerper, HECW1 antikoerper, Hecw1 antikoerper
- Hintergrund
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Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
Gene: HECW1
- Molekulargewicht
- 180kDa
- Gen-ID
- 23072
- UniProt
- Q76N89
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