POLR3K Antikörper (AA 1-108) (HRP)
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- Target Alle POLR3K Antikörper anzeigen
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
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Bindungsspezifität
- AA 1-108
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POLR3K Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human DNA-directed RNA polymerase III subunit RPC10 protein (1-108AA)
- Isotyp
- IgG
- Top Product
- Discover our top product POLR3K Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
- Andere Bezeichnung
- POLR3K (POLR3K Produkte)
- Synonyme
- MGC108467 antikoerper, POLR3K antikoerper, 12.3kDa antikoerper, 1500004O14Rik antikoerper, AI196849 antikoerper, AU014893 antikoerper, C11 antikoerper, RPC10 antikoerper, RPC11 antikoerper, C11-RNP3 antikoerper, RPC12.5 antikoerper, hRPC11 antikoerper, RNA polymerase III subunit K antikoerper, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog antikoerper, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antikoerper, polymerase (RNA) III (DNA directed) polypeptide K antikoerper, Polr3k antikoerper, polr3k.S antikoerper, polr3k antikoerper, POLR3K antikoerper
- Hintergrund
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Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Aliases: C11 antibody, C11 RNP3 antibody, DNA directed RNA polymerase III subunit K antibody, DNA directed RNA polymerase III subunit RPC10 antibody, DNA directed RNA polymerases III 12.5 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit K antibody, DNA-directed RNA polymerase III subunit RPC10 antibody, hRPC11 antibody, HsC11p antibody, My010 antibody, POLR3K antibody, Polymerase (RNA) III (DNA directed) polypeptide K antibody, Polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antibody, RNA polymerase III 12.5 kDa subunit antibody, RNA polymerase III subunit (hRPC11) antibody, RNA polymerase III subunit C10 antibody, RNA polymerase III subunit C11 antibody, RNA polymerase III subunit CII antibody, RPC10 antibody, RPC10_HUMAN antibody, RPC11 antibody, RPC12.5 antibody
- UniProt
- Q9Y2Y1
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