POLR3K Antikörper (AA 1-108) (FITC)

Produktnummer ABIN7150452

Produktdetails anti-POLR3K Antikörper (FITC)

Target: POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))

Bindungsspezifität: AA 1-108

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR3K Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA-directed RNA polymerase III subunit RPC10 protein (1-108AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu POLR3K

Target: POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))

Andere Bezeichnung: POLR3K (POLR3K Produkte)

Synonyme: MGC108467 antikoerper, POLR3K antikoerper, 12.3kDa antikoerper, 1500004O14Rik antikoerper, AI196849 antikoerper, AU014893 antikoerper, C11 antikoerper, RPC10 antikoerper, RPC11 antikoerper, C11-RNP3 antikoerper, RPC12.5 antikoerper, hRPC11 antikoerper, RNA polymerase III subunit K antikoerper, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog antikoerper, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antikoerper, polymerase (RNA) III (DNA directed) polypeptide K antikoerper, Polr3k antikoerper, polr3k.S antikoerper, polr3k antikoerper, POLR3K antikoerper

Hintergrund:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Aliases: C11 antibody, C11 RNP3 antibody, DNA directed RNA polymerase III subunit K antibody, DNA directed RNA polymerase III subunit RPC10 antibody, DNA directed RNA polymerases III 12.5 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit K antibody, DNA-directed RNA polymerase III subunit RPC10 antibody, hRPC11 antibody, HsC11p antibody, My010 antibody, POLR3K antibody, Polymerase (RNA) III (DNA directed) polypeptide K antibody, Polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antibody, RNA polymerase III 12.5 kDa subunit antibody, RNA polymerase III subunit (hRPC11) antibody, RNA polymerase III subunit C10 antibody, RNA polymerase III subunit C11 antibody, RNA polymerase III subunit CII antibody, RPC10 antibody, RPC10_HUMAN antibody, RPC11 antibody, RPC12.5 antibody

UniProt: Q9Y2Y1