XRCC3 Antikörper (AA 1-316) (FITC)

Produktnummer ABIN7150303

Produktdetails anti-XRCC3 Antikörper (FITC)

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Bindungsspezifität: AA 1-316

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XRCC3 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA repair protein XRCC3 protein (1-316AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu XRCC3

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Andere Bezeichnung: XRCC3 (XRCC3 Produkte)

Synonyme: CMM6 antikoerper, 4432412E01Rik antikoerper, AI182522 antikoerper, AW537713 antikoerper, MGC69118 antikoerper, im:7142103 antikoerper, zgc:101608 antikoerper, si:dkey-11b8.1 antikoerper, xrcc3 antikoerper, XRCC3 antikoerper, X-ray repair cross complementing 3 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 3 antikoerper, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antikoerper, XRCC3 antikoerper, Xrcc3 antikoerper, xrcc3.L antikoerper, xrcc3 antikoerper

Hintergrund:

Background: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment, the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junctions of replication forks. Involved in HJ resolution and thus in processing HR intermediates late in the DNA repair process, the function may be linked to the CX3 complex and seems to involve GEN1 during mitotic cell cycle progression. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.

Aliases: CMM6 antibody, DNA repair protein XRCC3 antibody, RAD51 like antibody, X ray repair complementing defective repair in Chinese hamster antibody, X ray repair complementing defective repair in Chinese hamster cells 3 antibody, X ray repair cross complementing protein 3 antibody, X-ray repair cross-complementing protein 3 antibody, XRCC 3 antibody, XRCC3 antibody, XRCC3_HUMAN antibody

UniProt: O43542

Pathways: DNA Reparatur