CDK5RAP2 Antikörper (Regulatory Subunit) (HRP)

Produktnummer ABIN7147233

Produktdetails anti-CDK5RAP2 Antikörper (HRP)

Target: CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))

Bindungsspezifität: AA 996-1111, Regulatory Subunit

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK5RAP2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human CDK5 regulatory subunit-associated protein 2 protein (996-1111AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CDK5RAP2

Target: CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))

Andere Bezeichnung: CDK5RAP2 (CDK5RAP2 Produkte)

Synonyme: EGFL5 antikoerper, C48 antikoerper, Cep215 antikoerper, MCPH3 antikoerper, 2900018K03Rik antikoerper, an antikoerper, mKIAA1633 antikoerper, CDK5 regulatory subunit associated protein 2 antikoerper, CDK5 regulatory subunit-associated protein 2 antikoerper, CDK5RAP2 antikoerper, LOC100156240 antikoerper, cdk5rap2 antikoerper, Cdk5rap2 antikoerper

Hintergrund:

Background: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of a gamma-tubulin ring complex onto centrosomes (PubMed:26485573).

Aliases: C48 antibody, CDK5 activator-binding protein C48 antibody, CDK5 regulatory subunit associated protein 2 antibody, CDK5 regulatory subunit-associated protein 2 antibody, CDK5RAP2 antibody, centrosomal protein 215 kDa antibody, Centrosome-associated protein 215 antibody, CEP215 antibody, CK5P2_HUMAN antibody, MCPH3 antibody

UniProt: Q96SN8

Pathways: M Phase, SARS-CoV-2 Protein Interaktom