Casein Kinase 1 gamma 2 Antikörper (Isoform gamma 2)
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- Target Alle Casein Kinase 1 gamma 2 (CSNK1G2) Antikörper anzeigen
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
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Bindungsspezifität
- AA 316-415, Isoform gamma 2
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Casein Kinase 1 gamma 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
- Kreuzreaktivität
- Human, Maus
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Casein kinase I isoform gamma-2 protein (316-415AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
- Andere Bezeichnung
- CSNK1G2 (CSNK1G2 Produkte)
- Synonyme
- CK1g2 antikoerper, 2810429I12Rik antikoerper, AI463719 antikoerper, CKI antikoerper, ck1-gamma antikoerper, CSNK1G2 antikoerper, ck1g2 antikoerper, csnk1g2 antikoerper, fj97g11 antikoerper, wu:fj97g11 antikoerper, wz8345 antikoerper, zgc:110719 antikoerper, zgc:153415 antikoerper, casein kinase 1 gamma 2 antikoerper, casein kinase 1, gamma 2 antikoerper, casein kinase 1 gamma 2 L homeolog antikoerper, casein kinase 1, gamma 2a antikoerper, casein kinase 1, gamma 2b antikoerper, CSNK1G2 antikoerper, Csnk1g2 antikoerper, csnk1g2.L antikoerper, csnk1g2 antikoerper, csnk1g2a antikoerper, csnk1g2b antikoerper
- Hintergrund
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Background: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.
Aliases: Casein kinase 1, gamma 2 antibody, Casein kinase I isoform gamma 2 antibody, Casein kinase I isoform gamma-2 antibody, CK1g2 antibody, CKI gamma 2 antibody, CKI-gamma 2 antibody, CSNK1G 2 antibody, Csnk1g2 antibody, KC1G2_HUMAN antibody
- UniProt
- P78368
- Pathways
- Hedgehog Signalweg
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