ASNA1 Antikörper (AA 1-348)

Produktnummer ABIN7145033

Produktdetails anti-ASNA1 Antikörper

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Bindungsspezifität: AA 1-348

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASNA1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human ATPase ASNA1 protein (1-348AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ASNA1

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Andere Bezeichnung: ASNA1 (ASNA1 Produkte)

Synonyme: ARSA-I antikoerper, ARSA1 antikoerper, ASNA-I antikoerper, GET3 antikoerper, TRC40 antikoerper, hASNA-I antikoerper, 1810048H22Rik antikoerper, ArsA antikoerper, wu:fd05d03 antikoerper, zgc:56540 antikoerper, zgc:86799 antikoerper, arsa-i antikoerper, arsa1 antikoerper, ASNA1 antikoerper, asna1 antikoerper, MGC146316 antikoerper, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) antikoerper, arsenical pump-driving ATPase antikoerper, pseudo antikoerper, ATPase ASNA1 homolog antikoerper, arsenite-translocating ATPase; arsenical resistance ATPase; arsenite-transporting ATPase antikoerper, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) S homeolog antikoerper, L-asparaginase antikoerper, ATPase asna-1 antikoerper, ASNA1 antikoerper, ATEG_04670 antikoerper, arsA2 antikoerper, arsA antikoerper, HCAG_00048 antikoerper, LOC5574421 antikoerper, CC1G_08655 antikoerper, CpipJ_CPIJ005690 antikoerper, PTRG_02265 antikoerper, pKlebpneu12_p77 antikoerper, UREG_07455 antikoerper, BDBG_06308 antikoerper, MCYG_00630 antikoerper, LOC100284977 antikoerper, Asna1 antikoerper, asna1 antikoerper, asna1.S antikoerper, MGYG_01332 antikoerper, asnA1 antikoerper, Tsp_06776 antikoerper, asna-1 antikoerper

Hintergrund:

Background: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.

Aliases: ARSA 1 antibody, ARSA antibody, ArsA arsenite transporter ATP binding homolog 1 antibody, ArsA arsenite transporter, ATP binding, E. coli, homolog of, 1 antibody, ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial) antibody, ARSA I antibody, ARSA-I antibody, ARSA1 antibody, ARSAI antibody, Arsenical pump driving ATPase antibody, Arsenical pump-driving ATPase antibody, Arsenical resistance ATPase antibody, Arsenite translocating ATPase antibody, Arsenite transporting ATPase antibody, Arsenite-stimulated ATPase antibody, ASNA 1 antibody, ASNA I antibody, ASNA-I antibody, ASNA_HUMAN antibody, ASNA1 antibody, Asna1 protein antibody, ASNAI antibody, ATPase ASNA1 antibody, GET3 antibody, Golgi to ER traffic 3 homolog antibody, hARSA-I antibody, hASNA-I antibody, MGC3821 antibody, Transmembrane domain recognition complex 40 kDa ATPase subunit antibody, Transmembrane domain recognition complex, 40 kDa antibody, TRC40 antibody

UniProt: O43681

Pathways: Positive Regulation of Peptide Hormone Secretion