ASNA1 Antikörper

Produktnummer ABIN7254112

Produktdetails anti-ASNA1 Antikörper

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASNA1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human ASNA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.26 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ASNA1

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Andere Bezeichnung: ASNA1 (ASNA1 Produkte)

Synonyme: ARSA-I antikoerper, ARSA1 antikoerper, ASNA-I antikoerper, GET3 antikoerper, TRC40 antikoerper, hASNA-I antikoerper, 1810048H22Rik antikoerper, ArsA antikoerper, wu:fd05d03 antikoerper, zgc:56540 antikoerper, zgc:86799 antikoerper, arsa-i antikoerper, arsa1 antikoerper, ASNA1 antikoerper, asna1 antikoerper, MGC146316 antikoerper, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) antikoerper, arsenical pump-driving ATPase antikoerper, pseudo antikoerper, ATPase ASNA1 homolog antikoerper, arsenite-translocating ATPase; arsenical resistance ATPase; arsenite-transporting ATPase antikoerper, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) S homeolog antikoerper, L-asparaginase antikoerper, ATPase asna-1 antikoerper, ASNA1 antikoerper, ATEG_04670 antikoerper, arsA2 antikoerper, arsA antikoerper, HCAG_00048 antikoerper, LOC5574421 antikoerper, CC1G_08655 antikoerper, CpipJ_CPIJ005690 antikoerper, PTRG_02265 antikoerper, pKlebpneu12_p77 antikoerper, UREG_07455 antikoerper, BDBG_06308 antikoerper, MCYG_00630 antikoerper, LOC100284977 antikoerper, Asna1 antikoerper, asna1 antikoerper, asna1.S antikoerper, MGYG_01332 antikoerper, asnA1 antikoerper, Tsp_06776 antikoerper, asna-1 antikoerper

Hintergrund: ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth,increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition,ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.

UniProt: O43681

Pathways: Positive Regulation of Peptide Hormone Secretion