ALOX12B Antikörper (AA 484-663) (HRP)
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- Target Alle ALOX12B Antikörper anzeigen
- ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B))
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Bindungsspezifität
- AA 484-663
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ALOX12B Antikörper ist konjugiert mit HRP
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Applikation
- ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Arachidonate 12-lipoxygenase, 12R-type protein (484-663AA)
- Isotyp
- IgG
- Top Product
- Discover our top product ALOX12B Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B))
- Andere Bezeichnung
- ALOX12B (ALOX12B Produkte)
- Synonyme
- ALOX12B antikoerper, MGC107915 antikoerper, MGC85124 antikoerper, 12R-LOX antikoerper, ARCI2 antikoerper, Aloxe2 antikoerper, e-LOX2 antikoerper, arachidonate 12-lipoxygenase, 12R type antikoerper, arachidonate 12-lipoxygenase, 12R type S homeolog antikoerper, ALOX12B antikoerper, alox12b antikoerper, alox12b.S antikoerper, Alox12b antikoerper
- Hintergrund
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Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12R)-hydroperoxyeicosatetraenoic acid/(12R)-HPETE and minor stereoisomers. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. May also play a role in the regulation of the expression of airway mucins.
Aliases: ALOX12B antibody, Arachidonate 12-lipoxygenase antibody, 12R-type antibody, 12R-LOX antibody, 12R-lipoxygenase antibody, EC 1.13.11.- antibody, Epidermis-type lipoxygenase 12 antibody
- UniProt
- O75342
- Pathways
- Cell-Cell Junction Organization
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