ADCY1 Antikörper (AA 897-1136)

Produktnummer ABIN7143324

Produktdetails anti-ADCY1 Antikörper

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Bindungsspezifität: AA 897-1136

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADCY1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Adenylate cyclase type 10 protein (897-1136AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ADCY1

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Andere Bezeichnung: ADCY1 (ADCY1 Produkte)

Synonyme: AC1 antikoerper, D11Bwg1392e antikoerper, I-AC antikoerper, brl antikoerper, mKIAA4070 antikoerper, Ac1 antikoerper, adenylate cyclase 1 antikoerper, adenylate cyclase type 1 antikoerper, adenylate cyclase 1 (brain) antikoerper, ADCY1 antikoerper, LOC100449504 antikoerper, adcy1 antikoerper, Adcy1 antikoerper

Hintergrund:

Background: Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation (PubMed:17591988).

Aliases: ADCY10 antibody, SAC antibody, Adenylate cyclase type 10 antibody, EC 4.6.1.1 antibody, AH-related protein antibody, Adenylate cyclase homolog antibody, Germ cell soluble adenylyl cyclase antibody, hsAC antibody, sAC antibody, Testicular soluble adenylyl cyclase antibody

UniProt: Q96PN6

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma