ARPC3 Antikörper (AA 2-175)
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- Target Alle ARPC3 Antikörper anzeigen
- ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))
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Bindungsspezifität
- AA 2-175
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ARPC3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))
- Andere Bezeichnung
- ARPC3 (ARPC3 Produkte)
- Synonyme
- ARC21 antikoerper, p21-Arc antikoerper, 1110006A04Rik antikoerper, 21kDa antikoerper, AA408672 antikoerper, AI788639 antikoerper, p21-Ar antikoerper, p21Arc antikoerper, arc21 antikoerper, p21-arc antikoerper, zgc:86828 antikoerper, actin related protein 2/3 complex subunit 3 antikoerper, actin related protein 2/3 complex, subunit 3 antikoerper, actin related protein 2/3 complex subunit 3 L homeolog antikoerper, actin related protein 2/3 complex, subunit 3, 21kDa antikoerper, actin related protein 2/3 complex subunit 3 pseudogene antikoerper, actin-related protein 2/3 complex subunit 3 antikoerper, actin-related protein 2/3 complex subunit 3 pseudogene antikoerper, ARPC3 antikoerper, Arpc3 antikoerper, arpc3.L antikoerper, LOC738738 antikoerper, arpc3 antikoerper, LOC100036831 antikoerper, LOC100341254 antikoerper
- Hintergrund
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Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Aliases: ARPC3 antibody, ARC21Actin-related protein 2/3 complex subunit 3 antibody, Arp2/3 complex 21 kDa subunit antibody, p21-ARC antibody
- UniProt
- O15145
- Pathways
- RTK Signalweg, Regulation of Actin Filament Polymerization
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