ARPC3 Antikörper (AA 2-175)

Produktnummer ABIN7143089

Produktdetails anti-ARPC3 Antikörper

Target: ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))

Bindungsspezifität: AA 2-175

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARPC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARPC3

Target: ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))

Andere Bezeichnung: ARPC3 (ARPC3 Produkte)

Synonyme: ARC21 antikoerper, p21-Arc antikoerper, 1110006A04Rik antikoerper, 21kDa antikoerper, AA408672 antikoerper, AI788639 antikoerper, p21-Ar antikoerper, p21Arc antikoerper, arc21 antikoerper, p21-arc antikoerper, zgc:86828 antikoerper, actin related protein 2/3 complex subunit 3 antikoerper, actin related protein 2/3 complex, subunit 3 antikoerper, actin related protein 2/3 complex subunit 3 L homeolog antikoerper, actin related protein 2/3 complex, subunit 3, 21kDa antikoerper, actin related protein 2/3 complex subunit 3 pseudogene antikoerper, actin-related protein 2/3 complex subunit 3 antikoerper, actin-related protein 2/3 complex subunit 3 pseudogene antikoerper, ARPC3 antikoerper, Arpc3 antikoerper, arpc3.L antikoerper, LOC738738 antikoerper, arpc3 antikoerper, LOC100036831 antikoerper, LOC100341254 antikoerper

Hintergrund:

Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).

Aliases: ARPC3 antibody, ARC21Actin-related protein 2/3 complex subunit 3 antibody, Arp2/3 complex 21 kDa subunit antibody, p21-ARC antibody

UniProt: O15145

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization