MAGED1 Antikörper

Produktnummer ABIN7140275

Produktdetails anti-MAGED1 Antikörper

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MAGED1

Target: MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))

Andere Bezeichnung: Maged1 (MAGED1 Produkte)

Synonyme: MAGED1 antikoerper, DLXIN-1 antikoerper, NRAGE antikoerper, 2810433C11Rik antikoerper, 5430405L04Rik antikoerper, DXBwg1492e antikoerper, Dlixin antikoerper, Dlxin-1 antikoerper, Dlxin1 antikoerper, MAGE-D1 antikoerper, mFLJ00163 antikoerper, Nrage antikoerper, MAGE family member D1 antikoerper, melanoma antigen family D, 1 antikoerper, melanoma antigen, family D, 1 antikoerper, MAGED1 antikoerper, Maged1 antikoerper

Hintergrund:

Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.

Zhao Z,et al.(2002) Sci China C Life Sci.45(4):412-20.
Shen WG,et al.(2007) Cell Commun Adhes.14(1):21-31.
Cheresh DA,et al. (1984) J Biol Chem.259(12):7453-9.

Aliases: Maged1 antibody, Nrage antibody, Melanoma-associated antigen D1 antibody, Dlxin-1 antibody, MAGE-D1 antigen antibody, Neurotrophin receptor-interacting MAGE homolog antibody

UniProt: Q9QYH6

Pathways: Neurotrophin Signalübertragung