TRKB Antikörper (pTyr515)

Produktnummer ABIN7139018

Produktdetails anti-TRKB Antikörper

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Bindungsspezifität: pTyr515

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRKB Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 515 (P-Q-Y(p)-F-G) derived from Human TrkB.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF:1:100-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRKB

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Andere Bezeichnung: NTRK2 (NTRK2 Produkte)

Synonyme: trkb antikoerper, trkb-b antikoerper, xtrkb antikoerper, si:ch211-220b11.1 antikoerper, trkB2 antikoerper, NTRK2 antikoerper, ntrk2 antikoerper, gp145-trkb antikoerper, TRKB antikoerper, GP145-TrkB antikoerper, trk-B antikoerper, AI848316 antikoerper, C030027L06Rik antikoerper, Tkrb antikoerper, trkB antikoerper, RATTRKB1 antikoerper, TRKB1 antikoerper, Trk-B antikoerper, TrkB antikoerper, neurotrophic receptor tyrosine kinase 2 antikoerper, neurotrophic receptor tyrosine kinase 2 L homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2b antikoerper, neurotrophic receptor tyrosine kinase 2 S homeolog antikoerper, neurotrophic tyrosine kinase, receptor, type 2 antikoerper, NTRK2 antikoerper, ntrk2.L antikoerper, ntrk2b antikoerper, ntrk2.S antikoerper, ntrk2 antikoerper, Ntrk2 antikoerper

Hintergrund:

Background: Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

Woronowicz A, et al. Glycobiology. 2007 Jan,17(1):10-24.
Mojsilovic-Petrovic J, et al. J Neurosci. 2006 Sep 6,26(36):9250-63.
Lewis MA, et al. Mol Pharmacol. 2006 Apr,69(4):1396-404.
Cai D, et al. Physiol Genomics. 2006 Feb 14,24(3):191-7.

Aliases: AI848316 antibody, BDNF tropomyosine receptor kinase B antibody, BDNF/NT 3 growth factors receptor antibody, BDNF/NT-3 growth factors receptor antibody, Brain derived neurotrophic factor receptor antibody, C030027L06Rik antibody, EC 2.7.10.1 antibody, GP145 TrkB antibody, GP145-TrkB antibody, GP145-TrkB/GP95-TrkB antibody, GP95 TrkB antibody, Neurotrophic receptor tyrosine kinase 2 antibody, Neurotrophic tyrosine kinase receptor type 2 antibody, Neurotrophin receptor tyrosine kinase type 2 antibody, NTRK 2 antibody, Ntrk2 antibody, NTRK2_HUMAN antibody, Obesity, hyperphagia, and developmental delay, included antibody, RATTRKB1 antibody, Tkrb antibody, Trk B antibody, Trk-B antibody, TRKB antibody, TrkB tyrosine kinase antibody, TRKB1 antibody, Tropomyosin related kinase B antibody, tyrosine kinase receptor B antibody, Tyrosine receptor kinase B antibody

UniProt: Q16620

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport