EPOR Antikörper (pTyr368)
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- Target Alle EPOR Antikörper anzeigen
- EPOR (Erythropoietin Receptor (EPOR))
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Bindungsspezifität
- pTyr368
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPOR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y(p)-L-V) derived from Human Epo-R.
- Isotyp
- IgG
- Top Product
- Discover our top product EPOR Primärantikörper
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anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 3D10 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 301-450) antibodyEPOR Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 470-504), (C-Term) antibodyEPOR Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB50846 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 45-244) antibodyEPOR Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibodyEPOR Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3F6 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 274-508) antibodyEPOR Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 320-506) antibodyEPOR Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR Reaktivität: Human FACS, cELISA Wirt: Maus Monoclonal VP-2E8 unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB:1:500-1:1000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- EPOR (Erythropoietin Receptor (EPOR))
- Andere Bezeichnung
- EPOR (EPOR Produkte)
- Synonyme
- EPOR antikoerper, epor antikoerper, EPO-R antikoerper, erythropoietin receptor antikoerper, erythropoietin receptor L homeolog antikoerper, EPOR antikoerper, epor antikoerper, Epor antikoerper, epor.L antikoerper
- Hintergrund
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Background:
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
Funakoshi-Tago M, et al. (2010) J Biol Chem 285, 5296-307
Sulahian R, Cleaver O, Huang LJ (2009) Blood 113, 5287-97
Zhang YL, et al. (2009) Mol Cell 33, 266-74Aliases: EPO R antibody, EPO Receptor antibody, EPO-R antibody, epor antibody, EPOR_HUMAN antibody, Erythropoietin receptor antibody, Erythropoietin receptor precursor antibody, MGC138358 antibody
- UniProt
- P19235
- Pathways
- JAK-STAT Signalweg
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