HDAC8 Antikörper (pSer39)

Produktnummer ABIN7138593

Produktdetails anti-HDAC8 Antikörper

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Bindungsspezifität: pSer39

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC8 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100, IF:1:100-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Andere Bezeichnung: HDAC8 (HDAC8 Produkte)

Synonyme: HD8 antikoerper, CDLS5 antikoerper, HDACL1 antikoerper, MRXS6 antikoerper, RPD3 antikoerper, WTS antikoerper, 2610007D20Rik antikoerper, RGD1562895 antikoerper, wu:fd19a02 antikoerper, zgc:66196 antikoerper, ATHDA8 antikoerper, HDA8 antikoerper, HISTONE DEACETYLASE 8 antikoerper, T27G7.14 antikoerper, T27G7_14 antikoerper, histone deacetylase 8 antikoerper, histone deacetylase 8 antikoerper, histone deacetylase 8 L homeolog antikoerper, CC1G_05302 antikoerper, hdac8 antikoerper, HDAC8 antikoerper, Hdac8 antikoerper, hdac8.L antikoerper, HDA08 antikoerper

Hintergrund:

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Lee H, et al. (2004) Mol Cell Biol. 24(2): 765-773.

Aliases: CDA07 antibody, CDLS5 antibody, HD 8 antibody, HD8 antibody, HDAC 8 antibody, Hdac8 antibody, HDAC8_HUMAN antibody, HDACL 1 antibody, HDACL1 antibody, Histone deacetylase 8 antibody, Histone deacetylase like 1 antibody, MRXS6 antibody, RPD 3 antibody, RPD3 antibody, WTS antibody

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process