TP53BP1 Antikörper (pSer25)

Produktnummer ABIN7138510

Produktdetails anti-TP53BP1 Antikörper

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Bindungsspezifität: pSer25

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53BP1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 25 (E-D-S(p)-Q-P) derived from Human 53BP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TP53BP1

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Andere Bezeichnung: TP53BP1 (TP53BP1 Produkte)

Synonyme: TP53BP1 antikoerper, MGC160112 antikoerper, 53BP1 antikoerper, Tp53bp1 antikoerper, m53BP1 antikoerper, p202 antikoerper, Trp53bp1 antikoerper, tumor protein p53 binding protein 1 antikoerper, tumor suppressor p53-binding protein 1 antikoerper, tumor protein p53 binding protein 1 (predicted), 5 prime antikoerper, transformation related protein 53 binding protein 1 antikoerper, TP53BP1 antikoerper, tp53bp1 antikoerper, LOC100550605 antikoerper, Trp53bp1 antikoerper, Tp53bp1 antikoerper

Hintergrund:

Background: Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

Aliases: 53 BP1 antibody, 53BP1 antibody, FLJ41424 antibody, MGC138366 antibody, p202 antibody, p53 binding protein 1 antibody, p53 BP1 antibody, p53-binding protein 1 antibody, p53BP1 antibody, TP53 BP1 antibody, TP53B_HUMAN antibody, Tp53bp1 antibody, TRP53 BP1 antibody, Tumor protein 53 binding protein 1 antibody, Tumor protein p53 binding protein 1 antibody, Tumor suppressor p53 binding protein 1 antibody, Tumor suppressor p53-binding protein 1 antibody

UniProt: Q12888

Pathways: DNA Reparatur