DNAJB6 Antikörper (AA 1-100)

Produktnummer ABIN708146

Produktdetails anti-DNAJB6 Antikörper

Target: DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

Bindungsspezifität: AA 1-100

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJB6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSJ2/DNAJB6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DNAJB6

Target: DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

Andere Bezeichnung: DNAJB6 (DNAJB6 Produkte)

Synonyme: DJ4 antikoerper, DnaJ antikoerper, HHDJ1 antikoerper, HSJ-2 antikoerper, HSJ2 antikoerper, LGMD1E antikoerper, MRJ antikoerper, MSJ-1 antikoerper, Mrj antikoerper, mDj4 antikoerper, dnajb6 antikoerper, zgc:56709 antikoerper, hsj2 antikoerper, DnaJ heat shock protein family (Hsp40) member B6 antikoerper, DnaJ (Hsp40) homolog, subfamily B, member 6b antikoerper, DnaJ heat shock protein family (Hsp40) member B6 S homeolog antikoerper, DnaJ heat shock protein family (Hsp40) member B6 L homeolog antikoerper, DNAJB6 antikoerper, Dnajb6 antikoerper, dnajb6b antikoerper, dnajb6.S antikoerper, dnajb6.L antikoerper

Hintergrund:

Synonyms: DJ4, DnaJ, DNAJ B6, DnaJ homolog subfamily B member 6, DNAJB6, DNJB6_HUMAN, Heat shock protein J2, HHDJ1, HSJ-2, HSJ2, MRJ, MSJ-1, MSJ1.

Background: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Reduces huntingtin aggregation associated with HD. Also reduces cellular toxicity and caspase-3 activity.

Gen-ID: 10049