DNAJB6 Antikörper (AA 208-326)

Produktnummer ABIN7150528

Produktdetails anti-DNAJB6 Antikörper

Target: DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

Bindungsspezifität: AA 208-326

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJB6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DnaJ homolog subfamily B member 6 protein (208-326AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DNAJB6

Target: DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

Andere Bezeichnung: DNAJB6 (DNAJB6 Produkte)

Synonyme: DJ4 antikoerper, DnaJ antikoerper, HHDJ1 antikoerper, HSJ-2 antikoerper, HSJ2 antikoerper, LGMD1E antikoerper, MRJ antikoerper, MSJ-1 antikoerper, Mrj antikoerper, mDj4 antikoerper, dnajb6 antikoerper, zgc:56709 antikoerper, hsj2 antikoerper, DnaJ heat shock protein family (Hsp40) member B6 antikoerper, DnaJ (Hsp40) homolog, subfamily B, member 6b antikoerper, DnaJ heat shock protein family (Hsp40) member B6 S homeolog antikoerper, DnaJ heat shock protein family (Hsp40) member B6 L homeolog antikoerper, DNAJB6 antikoerper, Dnajb6 antikoerper, dnajb6b antikoerper, dnajb6.S antikoerper, dnajb6.L antikoerper

Hintergrund:

Background: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.

Aliases: DJ4 antibody, DnaJ antibody, DnaJ (Hsp40) homolog subfamily B member 6 antibody, DNAJ B6 antibody, DnaJ homolog subfamily B member 6 antibody, DnaJ like 2 protein antibody, DNAJB6 antibody, DNJB6_HUMAN antibody, Heat shock protein J2 antibody, HHDJ1 antibody, HSJ-2 antibody, HSJ2 antibody, LGMD1E antibody, MRJ antibody, MSJ-1 antibody, MSJ1 antibody

UniProt: O75190