ZFP36L2 Antikörper

Produktnummer ABIN7120985

Produktdetails anti-ZFP36L2 Antikörper

Target: ZFP36L2 (Zinc Finger Protein 36, C3H Type-Like 2 (ZFP36L2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFP36L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: zinc finger protein 36, C3H type-like 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ZFP36L2

Target: ZFP36L2 (Zinc Finger Protein 36, C3H Type-Like 2 (ZFP36L2))

Andere Bezeichnung: ZFP36L2 (ZFP36L2 Produkte)

Synonyme: BRF2 antikoerper, ERF-2 antikoerper, ERF2 antikoerper, RNF162C antikoerper, TIS11D antikoerper, Brf2 antikoerper, Tis11d antikoerper, fi22c11 antikoerper, wu:fi22c11 antikoerper, zgc:76924 antikoerper, ZFP36L2 antikoerper, XC3H-3 antikoerper, XC3H-3b antikoerper, c3h-3 antikoerper, zfp36l2 antikoerper, brf2 antikoerper, erf-2 antikoerper, erf2 antikoerper, rnf162c antikoerper, tis11d antikoerper, cb198 antikoerper, cb480 antikoerper, fk89d11 antikoerper, id:ibd1247 antikoerper, sb:cb198 antikoerper, sb:cb480 antikoerper, wu:fb80h11 antikoerper, wu:fb92f07 antikoerper, wu:fk89d11 antikoerper, zfp36l1 antikoerper, zgc:153979 antikoerper, XC3H-2 antikoerper, berg36 antikoerper, brf1 antikoerper, c3h-2 antikoerper, cmg1 antikoerper, erf-1 antikoerper, erf1 antikoerper, rnf162b antikoerper, tis11b antikoerper, zfp36l1-a antikoerper, zfp36l1-b antikoerper, ZFP36 ring finger protein like 2 antikoerper, zinc finger protein 36, C3H type-like 2 antikoerper, ZFP36 ring finger protein-like 2 S homeolog antikoerper, ZFP36 ring finger protein-like 2 L homeolog antikoerper, ZFP36 ring finger protein-like 2 antikoerper, zinc finger protein 36, C3H type-like 1a antikoerper, ZFP36 ring finger protein-like 1 L homeolog antikoerper, ZFP36L2 antikoerper, Zfp36l2 antikoerper, zfp36l2 antikoerper, zfp36l2.S antikoerper, zfp36l2.L antikoerper, zfp36l1a antikoerper, zfp36l1.L antikoerper

Hintergrund: Synonyms:BRF2, Butyrate response factor 2, EGF response factor 2, ERF 2, ERF2, Protein TIS11D, RNF162C, TIS11D, ZFP36L2 Background:mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element(ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation(PubMed:14981510). Specifically expressed in burst-forming unit-erythroid(BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation(By similarity).

Molekulargewicht: 51 kDa

Gen-ID: 678

UniProt: P47974

Pathways: Stem Cell Maintenance