TRPV6 Antikörper

Produktnummer ABIN7120140

Produktdetails anti-TRPV6 Antikörper

Target: TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPV6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: transient receptor potential cation channel, subfamily V, member 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IP: 1:200-1:1000, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu TRPV6

Target: TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))

Andere Bezeichnung: TRPV6 (TRPV6 Produkte)

Synonyme: ecac antikoerper, trpv5-6 antikoerper, TRPV6 antikoerper, trpv6 antikoerper, CaT antikoerper, ECaC antikoerper, ABP/ZF antikoerper, CAT1 antikoerper, CATL antikoerper, ECAC2 antikoerper, HSA277909 antikoerper, LP6728 antikoerper, ZFAB antikoerper, CAT antikoerper, CaT1 antikoerper, Cac antikoerper, Ecac2 antikoerper, Otrpc3 antikoerper, transient receptor potential cation channel, subfamily V, member 6 antikoerper, transient receptor potential cation channel subfamily V member 6 antikoerper, trpv6 antikoerper, TRPV6 antikoerper, Trpv6 antikoerper

Hintergrund: Synonyms:ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728, TRPV6, ZFAB Background:Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine(PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin(By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification(PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Molekulargewicht: 82 kDa,70 kDa

Gen-ID: 55503

UniProt: Q9H1D0

Pathways: T-Zell Rezeptor Signalweg