TRPV6 Antikörper (AA 620-764)

Produktnummer ABIN7172889

Produktdetails anti-TRPV6 Antikörper

Target: TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))

Bindungsspezifität: AA 620-764

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPV6 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Transient receptor potential cation channel subfamily V member 6 protein (620-764AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRPV6

Target: TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))

Andere Bezeichnung: TRPV6 (TRPV6 Produkte)

Synonyme: ecac antikoerper, trpv5-6 antikoerper, TRPV6 antikoerper, trpv6 antikoerper, CaT antikoerper, ECaC antikoerper, ABP/ZF antikoerper, CAT1 antikoerper, CATL antikoerper, ECAC2 antikoerper, HSA277909 antikoerper, LP6728 antikoerper, ZFAB antikoerper, CAT antikoerper, CaT1 antikoerper, Cac antikoerper, Ecac2 antikoerper, Otrpc3 antikoerper, transient receptor potential cation channel, subfamily V, member 6 antikoerper, transient receptor potential cation channel subfamily V member 6 antikoerper, trpv6 antikoerper, TRPV6 antikoerper, Trpv6 antikoerper

Hintergrund:

Background: Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin (By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Aliases: ABP/ZF antibody, ABPZF antibody, Alu binding protein with zinc finger domain antibody, Calcium channel CaT1 antibody, Calcium transport protein 1 antibody, CaT L antibody, CaT Like antibody, CaT-L antibody, CaT-like antibody, CaT1 antibody, ecac antibody, ECaC2 antibody, Epithelial apical membrane calcium transporter/channel CaT1 antibody, Epithelial calcium channel 2 antibody, Epithelial calcium channel antibody, HSA277909 antibody, LP6728 antibody, MGC162545 antibody, NUDC antibody, Transient receptor potential cation channel subfamily V member 6 antibody, TrpV6 antibody, TRPV6_HUMAN antibody, ZFAB antibody

UniProt: Q9H1D0

Pathways: T-Zell Rezeptor Signalweg