TJP1 Antikörper
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- Target Alle TJP1 Antikörper anzeigen
- TJP1 (Tight Junction Protein 1 (TJP1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TJP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- tight junction protein 1(zona occludens 1)
- Isotyp
- IgG
- Top Product
- Discover our top product TJP1 Primärantikörper
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- Applikationshinweise
- WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:50-1:200, IF: 1:20-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
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- Target
- TJP1 (Tight Junction Protein 1 (TJP1))
- Andere Bezeichnung
- ZO-1 (TJP1 Produkte)
- Synonyme
- ZO-1 antikoerper, ZO1 antikoerper, zo1 antikoerper, tight junction protein 1 antikoerper, tight junction protein ZO-1 antikoerper, TJP1 antikoerper, Tjp1 antikoerper, LOC396567 antikoerper
- Hintergrund
- Synonyms:Tight junction protein 1, Tight junction protein ZO 1, TJP1, ZO 1, ZO1, ZO-1, Zona occludens protein 1, Zonula occludens protein 1 Background:Tight junction(or zonula occludens) form the continuous intercellular barrier between epithelial and endothelial cells, which is required to separate tissue spaces and regulate selective movement of solutes across the epithelium and endothelium(PMID: 20066090). ZO-1(also known as TJP1) is a peripheral membrane phosphoprotein located on the cytoplasmic face and is expressed in tight junctions of both epithelial and endothelial cells(PMID: 3528172). It binds the transmembrane proteins occludin and the claudins linking them to cytoskeletal actin(PMID: 17418867). ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs(MAGUKs). It is a pivotal tight junction protein and may be involved in signalling mechanisms regulating cell proliferation and differentiation(PMID: 22782886).
- Molekulargewicht
- 230kd
- Gen-ID
- 7082
- UniProt
- Q07157
- Pathways
- Carbohydrate Homeostasis, Cell-Cell Junction Organization
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