ARHGEF1 Antikörper

Produktnummer ABIN7118488

Produktdetails anti-ARHGEF1 Antikörper

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: Rho guanine nucleotide exchange factor(GEF) 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ARHGEF1

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Andere Bezeichnung: ARHGEF1 (ARHGEF1 Produkte)

Synonyme: arhgef1 antikoerper, cb473 antikoerper, zgc:158261 antikoerper, ARHGEF1 antikoerper, GEF1 antikoerper, LBCL2 antikoerper, LSC antikoerper, P115-RHOGEF antikoerper, SUB1.5 antikoerper, Lbcl2 antikoerper, Lsc antikoerper, Rho guanine nucleotide exchange factor (GEF) 1a antikoerper, Rho guanine nucleotide exchange factor 1 antikoerper, Rho guanine nucleotide exchange factor (GEF) 1 antikoerper, arhgef1a antikoerper, ARHGEF1 antikoerper, arhgef1 antikoerper, Arhgef1 antikoerper

Hintergrund: Synonyms:ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5 Background:Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.

Molekulargewicht: 102-110 kDa

Gen-ID: 9138

UniProt: Q92888

Pathways: Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling