KLHL22 Antikörper
-
- Target Alle KLHL22 Antikörper anzeigen
- KLHL22 (Kelch-Like 22 (KLHL22))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser KLHL22 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Immunogen affinity purified
- Reinheit
- ≥95 % as determined by SDS-PAGE
- Immunogen
- kelch-like 22(Drosophila)
- Isotyp
- IgG
- Top Product
- Discover our top product KLHL22 Primärantikörper
-
-
- Applikationshinweise
- WB: 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Haltbarkeit
- 12 months
-
- Target
- KLHL22 (Kelch-Like 22 (KLHL22))
- Andere Bezeichnung
- KLHL22 (KLHL22 Produkte)
- Synonyme
- 2610318I18Rik antikoerper, Kelchl antikoerper, KELCHL antikoerper, RGD1306288 antikoerper, kelch-like 22 antikoerper, kelch like family member 22 antikoerper, kelch-like family member 22 antikoerper, Klhl22 antikoerper, KLHL22 antikoerper
- Hintergrund
- Synonyms: Background:Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint(SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
- Molekulargewicht
- 72 kDa
- Gen-ID
- 84861
- UniProt
- Q53GT1
-