HACE1 Antikörper

Produktnummer ABIN7114916

Produktdetails anti-HACE1 Antikörper

Target: HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HACE1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu HACE1

Target: HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))

Andere Bezeichnung: HACE1 (HACE1 Produkte)

Synonyme: HACE1 antikoerper, 1700042J16Rik antikoerper, A730034A22Rik antikoerper, BC025474 antikoerper, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 antikoerper, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 L homeolog antikoerper, HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 antikoerper, HACE1 antikoerper, hace1 antikoerper, hace1.L antikoerper, Hace1 antikoerper

Hintergrund: Synonyms:KIAA1320 Background:E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.

Molekulargewicht: 78 kDa

Gen-ID: 57531

UniProt: Q8IYU2