Fibrinogen beta Chain Antikörper

Produktnummer ABIN7114194

Produktdetails anti-Fibrinogen beta Chain Antikörper

Target: Fibrinogen beta Chain (FGB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: fibrinogen beta chain

Klon: 6F4

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Andere Bezeichnung: FGB (FGB Produkte)

Synonyme: FGB antikoerper, 2510049G14Rik antikoerper, DKFZp470D0312 antikoerper, LOC100223598 antikoerper, fibrinogen antikoerper, Ab1-216 antikoerper, Ac1-581 antikoerper, wu:fa55c11 antikoerper, zgc:77116 antikoerper, fgb antikoerper, fibrinogen beta chain antikoerper, fibrinogen beta chain L homeolog antikoerper, FGB antikoerper, Fgb antikoerper, fgb antikoerper, fgb.L antikoerper

Hintergrund: Synonyms:FGB, fibrinogen beta chain Background:Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha(FGA) and fibrinogen gamma(FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Molekulargewicht: 50 kDa

Gen-ID: 2244

UniProt: P02675