Fibrinogen beta Chain Antikörper (AA 202-491)
Kurzübersicht für Fibrinogen beta Chain Antikörper (AA 202-491) (ABIN3021950)
Target
Alle Fibrinogen beta Chain (FGB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 202-491
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Sequenz
- LENLRSKIQK LESDVSAQME YCRTPCTVSC NIPVVSGKEC EEIIRKGGET SEMYLIQPDS SVKPYRVYCD MNTENGGWTV IQNRQDGSVD FGRKWDPYKQ GFGNVATNTD GKNYCGLPGE YWLGNDKISQ LTRMGPTELL IEMEDWKGDK VKAHYGGFTV QNEANKYQIS VNKYRGTAGN ALMDGASQLM GENRTMTIHN GMFFSTYDRD NDGWLTSDPR KQCSKEDGGG WWYNRCHAAN PNGRYYWGGQ YTWDMAKHGT DDGVVWMNWK GSWYSMRKMS MKIRPFFPQQ
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 202-491 of human FGB (NP_005132.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Fibrinogen beta Chain (FGB)
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Andere Bezeichnung
- FGB
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Hintergrund
- The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FGB,HEL-S-78p,Cardiovascular,Blood,Coagulation,FGB
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Molekulargewicht
- 55 kDa
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Gen-ID
- 2244
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UniProt
- P02675
Target
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