ATP8A1 Antikörper

Produktnummer ABIN7111846

Produktdetails anti-ATP8A1 Antikörper

Target: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP8A1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ATPase, aminophospholipid transporter(APLT), class I, type 8A, member 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu ATP8A1

Target: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Andere Bezeichnung: ATP8A1 (ATP8A1 Produkte)

Synonyme: ATPASEII antikoerper, ATPIA antikoerper, ATPP2 antikoerper, AI481521 antikoerper, AI853962 antikoerper, APLT antikoerper, AW743152 antikoerper, AW822227 antikoerper, Atp3a2 antikoerper, B230107D19Rik antikoerper, ClassI antikoerper, mKIAA4233 antikoerper, ATPase phospholipid transporting 8A1 antikoerper, ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 antikoerper, Atp8a1 antikoerper, ATP8A1 antikoerper

Hintergrund: Synonyms:ATP8A1, ATPase II, ATPASEII, ATPIA, ATPP2, Chromaffin granule ATPase II Background:Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine(PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine(PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

Molekulargewicht: 120kd

Gen-ID: 10396

UniProt: Q9Y2Q0