ATP8A1 Antikörper (AA 448-545)

Produktnummer ABIN7163366

Produktdetails anti-ATP8A1 Antikörper

Target: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Bindungsspezifität: AA 448-545

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP8A1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phospholipid-transporting ATPase IA protein (448-545AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ATP8A1

Target: ATP8A1 (ATPase, Class I, Type 8A, Member 1 (ATP8A1))

Andere Bezeichnung: ATP8A1 (ATP8A1 Produkte)

Synonyme: ATPASEII antikoerper, ATPIA antikoerper, ATPP2 antikoerper, AI481521 antikoerper, AI853962 antikoerper, APLT antikoerper, AW743152 antikoerper, AW822227 antikoerper, Atp3a2 antikoerper, B230107D19Rik antikoerper, ClassI antikoerper, mKIAA4233 antikoerper, ATPase phospholipid transporting 8A1 antikoerper, ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 antikoerper, Atp8a1 antikoerper, ATP8A1 antikoerper

Hintergrund:

Background: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells.

Aliases: ATP8A1 antibody, ATPIAPhospholipid-transporting ATPase IA antibody, EC 7.6.2.1 antibody, ATPase class I type 8A member 1 antibody, Chromaffin granule ATPase II antibody, P4-ATPase flippase complex alpha subunit ATP8A1 antibody

UniProt: Q9Y2Q0