EDNRB Antikörper (AA 378-442)

Produktnummer ABIN705116

Produktdetails anti-EDNRB Antikörper

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Bindungsspezifität: AA 378-442

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDNRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Endolin B Receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-EDNRB Antikörper (ABIN705116)

Prayitnaningsih, Sujuti, Effendi, Abdullah, Anandita, Yohana, Permatasari, Widodo: "Neuropathy optic glaucomatosa induced by systemic hypertension through activation endothelin-1 signaling pathway in central retinal artery in rats." in: International journal of ophthalmology, Vol. 9, Issue 11, pp. 1568-1577, (2016) (PubMed).

Details zu EDNRB

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Andere Bezeichnung: ETBR/Endothelin B Receptor (EDNRB Produkte)

Synonyme: ABCDS antikoerper, ET-B antikoerper, ET-BR antikoerper, ETB antikoerper, ETBR antikoerper, ETRB antikoerper, HSCR antikoerper, HSCR2 antikoerper, WS4A antikoerper, Ednra antikoerper, Etb antikoerper, ETR-b antikoerper, ETb antikoerper, Sox10m1 antikoerper, EDNRB antikoerper, abcds antikoerper, etb antikoerper, etrb antikoerper, hscr antikoerper, hscr2 antikoerper, endothelin receptor type B antikoerper, EDNRB antikoerper, Ednrb antikoerper, ednrb antikoerper

Hintergrund:

Synonyms: ABCDS, Ednra, Ednrb, EDNRB_HUMAN, Endothelin B receptor, Endothelin B receptor precursor, Endothelin receptor Non selective type, Endothelin receptor non-selective type, Endothelin receptor type B, ET B, ET-B, ET-BR, ETB, ETRB, Hirschsprung disease 2, HSCR, HSCR2, EDNRB, HSCR, WS4A.

Background: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Gen-ID: 1910

UniProt: P24530

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process