EDNRB Antikörper (N-Term)

Produktnummer ABIN2854727

Produktdetails anti-EDNRB Antikörper

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDNRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to ETBR (endothelin receptor type B)
ETBR antibody [N1N2], N-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Endothelin B Receptor. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , H1299

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 50 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu EDNRB

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Andere Bezeichnung: endothelin receptor type B (EDNRB Produkte)

Synonyme: ABCDS antikoerper, ET-B antikoerper, ET-BR antikoerper, ETB antikoerper, ETBR antikoerper, ETRB antikoerper, HSCR antikoerper, HSCR2 antikoerper, WS4A antikoerper, Ednra antikoerper, Etb antikoerper, ETR-b antikoerper, ETb antikoerper, Sox10m1 antikoerper, EDNRB antikoerper, abcds antikoerper, etb antikoerper, etrb antikoerper, hscr antikoerper, hscr2 antikoerper, endothelin receptor type B antikoerper, EDNRB antikoerper, Ednrb antikoerper, ednrb antikoerper

Hintergrund: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct.

Cellular Localization: Cell membrane

Molekulargewicht: 50 kDa

Gen-ID: 1910

UniProt: P24530

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process