NGFR Antikörper (iFluor™647)

Produktnummer ABIN7077082

Produktdetails anti-NGFR Antikörper (iFluor™647)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NGFR Antikörper ist konjugiert mit iFluor™647

Applikation: Flow Cytometry (FACS)

Produktmerkmale: The clone ME20.4, a mouse monoclonal antibody selectively binds with a ~75 kD type I transmembrane protein known as CD271. It is also known as the nerve growth factor receptor (NGFR) and a member of the tumor necrosis factor receptor (TNFR) superfamily.  Various cell types express CD271 including neuronal axons, Schwann cells, mesenchymal stem cells, epithelial cells, etc.  Increased levels of CD271 were observed in brain metastatic melanoma cells and in lung-metastasizing melanoma cells. It is a transmembrane signaling receptor involved in negative cell cycle regulation and is specific for neural crest origin.

Aufreinigung: Purified

Reinheit: >95 %

Güteklasse: GMP Grade

Immunogen: WM245 melanoma cells

Klon: ME20-4

Isotyp: IgG1 kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Andere Bezeichnung: CD271 (NGFR Produkte)

Synonyme: ngfr antikoerper, wu:fb38c02 antikoerper, wu:fc10h01 antikoerper, CD271 antikoerper, Gp80-LNGFR antikoerper, TNFRSF16 antikoerper, p75(NTR) antikoerper, p75NTR antikoerper, LNGFR antikoerper, RNNGFRR antikoerper, Tnfrsf16 antikoerper, p75 antikoerper, NRH1b antikoerper, fullback antikoerper, nrh1 antikoerper, p75ntr antikoerper, tnfrsf16 antikoerper, p75NGFR antikoerper, nerve growth factor receptor antikoerper, neurotrophin receptor associated death domain antikoerper, nerve growth factor receptor S homeolog antikoerper, nerve growth factor receptor (TNFR superfamily, member 16) antikoerper, NGFR antikoerper, nradd antikoerper, Ngfr antikoerper, ngfr.S antikoerper

Hintergrund: The clone ME20.4, a mouse monoclonal antibody selectively binds with a ~75 kD type I transmembrane protein known as CD271. It is also known as the nerve growth factor receptor (NGFR) and a member of the tumor necrosis factor receptor (TNFR) superfamily.  Various cell types express CD271 including neuronal axons, Schwann cells, mesenchymal stem cells, epithelial cells, etc.  Increased levels of CD271 were observed in brain metastatic melanoma cells and in lung-metastasizing melanoma cells. It is a transmembrane signaling receptor involved in negative cell cycle regulation and is specific for neural crest origin.

Gen-ID: 4804

UniProt: P08138

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding