TNFRSF6B Antikörper

Produktnummer ABIN7076071

Produktdetails anti-TNFRSF6B Antikörper

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Human DcR3

Anwendungsinformationen

Applikationshinweise: WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:700-1:1400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TNFRSF6B

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Andere Bezeichnung: DcR3 (TNFRSF6B Produkte)

Synonyme: DCR3 antikoerper, DJ583P15.1.1 antikoerper, M68 antikoerper, M68E antikoerper, TR6 antikoerper, dcr3 antikoerper, m68 antikoerper, tr6 antikoerper, TNF receptor superfamily member 6b antikoerper, tumor necrosis factor receptor superfamily, member 11b antikoerper, regulator of telomere elongation helicase 1 antikoerper, TNF receptor superfamily member 6b L homeolog antikoerper, TNFRSF6B antikoerper, tnfrsf11b antikoerper, RTEL1 antikoerper, tnfrsf6b antikoerper, tnfrsf6b.L antikoerper

Hintergrund: Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.

Molekulargewicht: 33 kDa

Gen-ID: 8771

NCBI Accession: NP_003814

UniProt: O95407