TNFRSF6B Antikörper (N-Term)

Produktnummer ABIN499726

Produktdetails anti-TNFRSF6B Antikörper

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: DcR3 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DcR3 precursor.

Aufreinigung: Ion exchange chromatography

Immunogen: Human DcR3 (N-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1/500 to 1/1000. An approximately 33 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL.

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu TNFRSF6B

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Andere Bezeichnung: TNFRSF6B / DCR3 (TNFRSF6B Produkte)

Synonyme: DCR3 antikoerper, DJ583P15.1.1 antikoerper, M68 antikoerper, M68E antikoerper, TR6 antikoerper, dcr3 antikoerper, m68 antikoerper, tr6 antikoerper, TNF receptor superfamily member 6b antikoerper, tumor necrosis factor receptor superfamily, member 11b antikoerper, regulator of telomere elongation helicase 1 antikoerper, TNF receptor superfamily member 6b L homeolog antikoerper, TNFRSF6B antikoerper, tnfrsf11b antikoerper, RTEL1 antikoerper, tnfrsf6b antikoerper, tnfrsf6b.L antikoerper

Hintergrund: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively, (1,2). Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis (1,2). DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.Synonyms: Decoy receptor 3, Decoy receptor for Fas ligand

Gen-ID: 8771

UniProt: O95407