RGD1311563 antikoerper, 1300006C19Rik antikoerper, Simp antikoerper, SIMP antikoerper, STT3-B antikoerper, STT3B, catalytic subunit of the oligosaccharyltransferase complex antikoerper, STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae) antikoerper, Stt3b antikoerper, STT3B antikoerper
Hintergrund
STT3B is a component of the N-oligosaccharyl transferase (OST) enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3B seems to be involved in complex substrate specificity.