CYP11A1 Antikörper (AA 321-420)
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- Target Alle CYP11A1 Antikörper anzeigen
- CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
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Bindungsspezifität
- AA 321-420
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Reaktivität
- Human, Ratte, Maus, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP11A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Rind (Kuh), Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC
- Isotyp
- IgG
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- Applikationshinweise
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).
: "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." in: Toxicology letters, Vol. 284, pp. 46-55, (2018) (PubMed).
: "Prenatal exposure to bisphenol A disrupts adrenal steroidogenesis in adult mouse offspring." in: Environmental toxicology and pharmacology, Vol. 43, pp. 203-8, (2016) (PubMed).
: "Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis." in: Cell reports, Vol. 7, Issue 4, pp. 1130-42, (2014) (PubMed).
: "Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells." in: Reproductive biology and endocrinology : RB&E, Vol. 11, pp. 72, (2013) (PubMed).
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Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).
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- Target
- CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
- Andere Bezeichnung
- CYP11A1 (CYP11A1 Produkte)
- Synonyme
- CYP11A antikoerper, CYP11A1 antikoerper, CYPXIA1 antikoerper, P450SCC antikoerper, Cyp11a antikoerper, Cypxia1 antikoerper, D9Ertd411e antikoerper, P450scc antikoerper, Scc antikoerper, cscc antikoerper, P450(scc) antikoerper, SSC antikoerper, cytochrome P450 family 11 subfamily A member 1 antikoerper, cholesterol side-chain cleavage enzyme, mitochondrial-like antikoerper, cytochrome P450 cholesterol side-chain cleavage antikoerper, cytochrome P450, family 11, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 11, subfamily A, polypeptide 1 antikoerper, CYP11A1 antikoerper, LOC101827747 antikoerper, Cyp11a1 antikoerper
- Hintergrund
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Synonyms: CYP11A, CYPXIA1, P45SCC, Cholesterol side-chain cleavage enzyme, mitochondrial, Cholesterol desmolase, Cytochrome P45 11A1, Cytochrome P45(scc), CYP11A1
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
- Gen-ID
- 1583
- UniProt
- P05108
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
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