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CLEC9A Antikörper

CLEC9A Reaktivität: Human FACS, ICC Wirt: Maus Monoclonal 8F9 unconjugated
Produktnummer ABIN7013959
  • Target Alle CLEC9A Antikörper anzeigen
    CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
    Reaktivität
    • 51
    • 37
    • 15
    Human
    Wirt
    • 52
    • 13
    • 4
    • 2
    Maus
    Klonalität
    • 55
    • 15
    • 1
    Monoklonal
    Konjugat
    • 24
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CLEC9A Antikörper ist unkonjugiert
    Applikation
    • 55
    • 26
    • 26
    • 14
    • 13
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Spezifität
    The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Immunogen
    RBL-2H3 cells expressing human CLEC9A fused to an HA epitope
    Klon
    8F9
    Isotyp
    IgG2a
    Top Product
    Discover our top product CLEC9A Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))
    Andere Bezeichnung
    CD370 (CLEC9A Produkte)
    Hintergrund
    C-type lectin domain containing 9A,CD370 / CLEC9A, also known as DNGR1, is a type II transmembrane glycoprotein with extracellular C-type lectin domain and intracellular ITAM-containing domain. Its expression is restricted to BDCA3+ conventional dendritic cells and to a subset of CD14+ CD16- monocytes. CD370 serves as a receptor for ubiquitous preformed acid-labile protein associated ligands that are exposed when the cell membrane is damaged, such as on necrotic cells. Its triggering by these ligands mediates recruitment and activation of the tyrosine kinase Syk and leads to their cross-presentation to the immune system.,CLEC9A, DNGR1, DNGR-1, UNQ9341
    Gen-ID
    283420
    UniProt
    Q6UXN8
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