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CD80 Antikörper

CD80 Reaktivität: Maus, Hund FACS, IP, IHC (fro), Func Wirt: Armenischer Hamster Monoclonal 16-10A1 unconjugated
Produktnummer ABIN7013940
  • Target Alle CD80 Antikörper anzeigen
    CD80
    Reaktivität
    • 138
    • 107
    • 44
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Maus, Hund
    Wirt
    • 87
    • 71
    • 22
    • 18
    • 17
    • 1
    • 1
    Armenischer Hamster
    Klonalität
    • 137
    • 77
    • 2
    Monoklonal
    Konjugat
    • 85
    • 18
    • 17
    • 15
    • 13
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD80 Antikörper ist unkonjugiert
    Applikation
    • 127
    • 93
    • 69
    • 34
    • 34
    • 22
    • 14
    • 13
    • 13
    • 12
    • 11
    • 11
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    Spezifität
    The Armenian hamster monoclonal antibody 16-10A1 reacts with an extracellular epitope of CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Endotoxin-Niveau
    Low Endotoxin
    Immunogen
    CD80-transfected CHO cell line
    Klon
    16-10A1
    Isotyp
    IgG2
    Top Product
    Discover our top product CD80 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Functional application: Blocking.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    CD80
    Andere Bezeichnung
    CD80 (CD80 Produkte)
    Synonyme
    B7 antikoerper, B7-1 antikoerper, B7.1 antikoerper, BB1 antikoerper, CD28LG antikoerper, CD28LG1 antikoerper, LAB7 antikoerper, B71 antikoerper, Cd28l antikoerper, Ly-53 antikoerper, Ly53 antikoerper, MIC17 antikoerper, TSA1 antikoerper, CD80 molecule antikoerper, Cd80 molecule antikoerper, CD80 antigen antikoerper, CD80 antikoerper, Cd80 antikoerper
    Hintergrund
    CD80 Molecule,CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 Molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet, there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.,B7-1, BB1
    Gen-ID
    12519
    UniProt
    Q00609
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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