EXOC2 Antikörper

Produktnummer ABIN7264281

Produktdetails anti-EXOC2 Antikörper

Target: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human EXOC2 (NP_060773.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EXOC2

Target: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Andere Bezeichnung: EXOC2 (EXOC2 Produkte)

Synonyme: CG8843 antikoerper, Dmel\\CG8843 antikoerper, Sec-5 antikoerper, Sec5 antikoerper, Sec5p antikoerper, dsec5 antikoerper, SEC5 antikoerper, SEC5L1 antikoerper, 2410030I24Rik antikoerper, AI648199 antikoerper, Sec5l1 antikoerper, Rsec5 antikoerper, F7O12.2 antikoerper, F7O12_2 antikoerper, exocyst complex component sec5 antikoerper, Secretory 5 antikoerper, exocyst complex component 2 antikoerper, exocyst complex component sec5 antikoerper, Exocyst complex component 2 antikoerper, Sec5 antikoerper, EXOC2 antikoerper, Exoc2 antikoerper, SEC5A antikoerper, sec-5 antikoerper

Hintergrund: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 108 kDa

Calculated_MW: 104 kDa

Gen-ID: 55770

UniProt: Q96KP1

Pathways: Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis