EPS15L1 Antikörper

Produktnummer ABIN7263849

Produktdetails anti-EPS15L1 Antikörper

Target: EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPS15L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human EPS15L1 (NP_001245304.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EPS15L1

Target: EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))

Andere Bezeichnung: EPS15L1 (EPS15L1 Produkte)

Synonyme: Eps15R antikoerper, XEps15R antikoerper, EPS15R antikoerper, 9830147J04Rik antikoerper, AI593686 antikoerper, Eps15-rs antikoerper, epidermal growth factor receptor pathway substrate 15-like 1 S homeolog antikoerper, epidermal growth factor receptor pathway substrate 15 like 1 antikoerper, epidermal growth factor receptor pathway substrate 15-like 1 antikoerper, eps15l1.S antikoerper, EPS15L1 antikoerper, Eps15l1 antikoerper

Hintergrund: Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR), internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.

Molekulargewicht:

Observed_MW: 110 kDa

Calculated_MW: 66 kDa/83 kDa/94 kDa/99 kDa

Gen-ID: 58513

UniProt: Q9UBC2