EPS15L1 Antikörper (N-Term)

Produktnummer ABIN388934

Produktdetails anti-EPS15L1 Antikörper

Target: EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))

Bindungsspezifität: AA 186-216, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPS15L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EPS15R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-216 amino acids from the N-terminal region of human EPS15R.

Klon: RB4395

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu EPS15L1

Target: EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))

Andere Bezeichnung: EPS15R (EPS15L1 Produkte)

Synonyme: Eps15R antikoerper, XEps15R antikoerper, EPS15R antikoerper, 9830147J04Rik antikoerper, AI593686 antikoerper, Eps15-rs antikoerper, epidermal growth factor receptor pathway substrate 15-like 1 S homeolog antikoerper, epidermal growth factor receptor pathway substrate 15 like 1 antikoerper, epidermal growth factor receptor pathway substrate 15-like 1 antikoerper, eps15l1.S antikoerper, EPS15L1 antikoerper, Eps15l1 antikoerper

Hintergrund: Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment and shuttle to the 26S proteasome is a vital means of regulating the concentrations of key regulatory proteins in the cell by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include the activation of ubiquitin, an ATP-dependent formation of a thioester bond between ubiquitin and the enzyme E1, transfer by transacylation of ubiquitin from E1 to the ubiquitin conjugating enzyme E2, and covalent linkage to the target protein directly by E2 or via E3 ligase enzyme. Deubiquitination enzymes also exist to reverse the marking of protein substrates. Posttranslational tagging by Ub is involved in a multitude of cellular processes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, stress responses, the immune response, and nervous system functions.

Molekulargewicht: 94255

Gen-ID: 58513

NCBI Accession: NP_001245303, NP_001245304, NP_001245305, NP_067058

UniProt: Q9UBC2